Fibrillating Myocardium
نویسندگان
چکیده
منابع مشابه
Fibrillating myocardium : rabbit warren or beehive?
Until 20 years ago, it was thought that atrial and ventricular fibrillation were highly disorganized, with tens or hundreds of tiny wandering wavelets simultaneously present and following ever-changing pathways.1 In this model, the disorganization is due to intrinsic heterogeneity of refractory periods that causes transitory islets of refractoriness about which wavelets circulate. However, abou...
متن کاملMechanisms of the dynamics of reentry in a fibrillating myocardium. Developing a genes-to-rotors paradigm.
Because the myocardium was considered to behave structurally as a continuous medium, for many years attention focused on spatial variations in the membrane properties, which allow some cells to recover excitability faster as the mechanism for reentry.1 This mechanism still holds its place as a major underlying cause of many arrhythmias; eg, the long-QT syndrome.2 In the early 1980s, a second ge...
متن کاملThe fibrillating atrial myocardium. What can the detection of wave breaks tell us?
See article by Chen et al. [14] (pages 220 –232) in this circulating excitations to persist, was most likely responissue. sible for maintenance of the arrhythmia. In 1964, based on a simulation study, Moe and Abildskov formulated the Ventricular and atrial fibrillation have fascinated clinical classical ‘multiple-wavelet’ hypothesis to explain the cardiologists and cardiac scientists since the ...
متن کاملCalpains and cytokines in fibrillating human atria.
Atrial fibrillation (AF) is accompanied by intracellular calcium overload. The purpose of this study was to assess the role of calcium-dependent calpains and cytokines during AF. Atrial tissue samples from 32 patients [16 with chronic AF and 16 in sinus rhythm (SR)] undergoing open heart surgery were studied. Atrial expression of calpain I and II, calpastatin, troponin T (TnT), troponin C (TnC)...
متن کاملSustained reentry in the left ventricle of fibrillating pig hearts.
It has been proposed that ventricular fibrillation (VF) is driven by sustained reentry. However, mapping studies have not detected such "mother rotors" in large mammalian hearts. We mapped VF from three 21x12 unipolar electrode arrays in 6 pigs. Two of the arrays were adjacent to each other on the left-ventricular epicardium. Electrode spacing was 2 mm. The third array consisted of 21 needles (...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2000
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.86.4.369